SNIPER

Solid Tumor

Accurate quantification of tumor gene mutations and treatment-response monitoring with digital PCR — EGFR, HER2, ctHPV and more, from liquid biopsy and FFPE.

Explore Our Diagnostic Assays Portfolios

Available Tests: 8

Liquid Biopsy

EGFR Mutation Universal

Quantitative detection of seven common EGFR mutations is performed using digital PCR. This assay supports studies on drug selection and resistance monitoring in non-small cell lung cancer (NSCLC) treated with tyrosine kinase inhibitors (TKIs).
Sample
Peripheral blood, Tissue

EGFR Exon 21-L858R

Quantitative detection of the EGFR L858R mutation (exon 21) is performed using digital PCR. This assay supports studies on targeted therapy selection for NSCLC patients.
Sample
Peripheral blood, Tissue

EGFR Exon 20-T790M

Quantitative detection of the EGFR T790M mutation (exon 20) is performed using digital PCR. This assay supports studies on acquired resistance monitoring in NSCLC patients receiving TKI treatment.
Sample
Peripheral blood, Tissue

EGFR Exon 21-L861Q

Quantitative detection of the EGFR L861Q mutation (exon 21) is performed using digital PCR. This assay supports studies on drug guidance in NSCLC therapy.
Sample
Peripheral blood, Tissue

EGFR Exon 21-L858R & Exon 19-del

Quantitative detection of the EGFR Exon 21-L858R & Exon 19-deletion mutations is performed using digital PCR. This assay supports studies on targeted therapy decision-making in NSCLC.
Sample
Peripheral blood, Tissue

ctHPV Detection and Genotype

Quantitative detection of 14 high- and intermediate risk human papillomavirus (HPV) DNA types is performed using digital PCR in female plasma samples, including HPV 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68. Genotyping is supported, although HPV 59/68 and 56/66 are not differentiated. This assay supports studies on treatment response evaluation and recurrence monitoring related to minimal residual disease (MRD) in cervical cancer.
Sample
FFPE tissue, Peripheral blood

Thyroid 4-Gene (BRAF, RET, TP53, TERT)

Qualitative detection of BRAF, RET, TP53, and TERT gene mutations is performed using digital PCR in thyroid nodule samples of Bethesda category III and V. This assay supports studies on auxiliary classification of indeterminate thyroid lesions.
Sample
FFPE tissue, FNAB of thyroid nodules

HER2 Gene

Quantitative detection of HER2 gene copy number variation is performed using digital PCR. This assay supports studies on gene amplification, signal transduction, and targeted therapy research in breast cancer usind FFPE tissue sections.
Sample
FFPE tissue, Peripheral blood

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