2025 9 1.Blood Cancer Rapid Universal Detection of High-Risk and Low-Abundance Microbial Contaminations in CAR-T Cell Therapy 2.Solid Tumors CircNF1 modulates the progression and immune evasion of esophageal squamous cell carcinoma through dual regulation of PD-L1 Mapping Longitudinal Lung Mycobiome Characteristics of Severe COVID-19 patients, aprospective, multicenter cohort study 3.Infectious Diseases A stable cell line-based genomic DNA reference material for accurate HPV Development and validation of optimized lentivirus‑like particles for gene editing tool delivery with Gag‑Only strategy The circular RNA circANK suppresses rice resistance to bacterial blight by 1 inhibiting microRNA398b-mediated defense Establishment of pseudovirus reference material for human norovirus GII.4 4.Gene Therapy A Novel AAV Capsid-Mediated RS1 Gene Therapy Restored Retinal Function to Wild-Type Levels in Rs1R213W Mouse Model 5.Other Digital Melting Curve Analysis for Multiplex Quantification of Nucleic Acids on Droplet Digital PCR
2024 21 1.Blood Cancer COVID-19 mitigates the response to TKIs in patients with CML via the inhibition of T-cell immunity Usefulness of KIT mutant transcript levels for monitoring measurable residual disease Digital PCR-based GRHL2 methylation testing in acute myeloid leukemia diagnosis prognosis and monitoring(1) Establishment of reference measurement procedure and reference material for Treponema pallidum 2.Solid Tumors Establishment of potential reference measurement procedure and reference materials for EML 4-ALK fusion variants measurement 3.Infectious Diseases Multiplex Digital PCR-Based Development and discussion of the Detection of Genetic Association Between Staphylococcus aureus and mecA COVID-19 Rebound After VV116 vs Nirmatrelvir-Ritonavir Treatment A Randomized Clinical Trial Development of an Integrated Disposable Device for SARSCoV-2 Nucleic Acid Extraction and Detection Establishment and Application of Multiplex Droplet Digital PCR for SARS-CoV-2 Omicron Variant Development and evaluation of a triplex droplet digital PCR method for differentiation of M. tuberculosis, M. bovis and BCG Development of RT‑dPCR method and reference material for rotavirus G3P8 and G9P8 Establishment of digital PCR method and reference materials for porcine parvovirus detection 4.Methodology Establishment of a Sensitive and Reliable Droplet Digital PCR Assay for the Detection of Bursaphelenchus xylophilus Establishment of genomic RNA reference materials for BCR‑ABL1 P210 measurement 5.Prenatal Screening Development of a Multiplex ddPCR Detection Method for Accurate Non-Invasive Prenatal Testing of Trisomy 21 6.Genetic & Rare Diseases Identification and functional verification of Y‐chromosome‐specific gene typo‐gyf in 7.Other A high-throughput droplet digital PCR system aiming eight DNA methylation targets for age prediction Nanoparticle LDH enhances RNAi efficiency of dsRNA in piercing-sucking pests by promoting dsRNA stability and transport in plants Electrostatic microfiltration (EM) enriches and recovers viable microorganisms at low-abundance in large-volume samples and enhances downstream detection PlexinA1 PLXNA1 as a novel scaffold protein for the engineering of extracellular vesicles Doped carbon dots affect heavy metal speciation in mining soil changes of dissimilated iron reduction processes and microbial communities
2023 8 1.Blood Cancer Usefulness of KIT mutant transcript levels for monitoring measurable residual disease Mismatch-Guided Deoxyribonucleic Acid Assembly Enables Ultrasensitive and Multiplex Detection of Low-Allele-Fraction Variants in Clinical Samples Highly Sensitive Droplet Digital PCR for Detection of Low-level JAK2V617F Mutation 数字PCR与实时荧光定量PCR检测慢性髓性白血病患者BCR__ABL mRNA水平的比较性研究 2.Infectious Diseases Reference material development for detection of human respiratory syncytial virus using digital PCR Establishment of Digital PCR Method and Reference Material for Adenoviruses 40 and 41 3.Other Analysis of microbial diversity and volatile metabolites across different types of pit mud in sauce-flavored Baijiu based on nanopore sequencing and metabolomics QuantAS a comprehensive pipeline to study alternative splicing by absolute quantification
2022 Before 10 1.Blood Cancer Systemically Silencing Long Non-coding RNAs Maclpil With Short Interfering RNA Nanoparticles Alleviates Experimental Ischem A New Multiplex Genetic Detection Assay Method for the Rapid Semi-Quantitative Detection of Six Common Curable Sexually Transmitted Pathogens From 2.Infectious Diseases 利用实时荧光定量PCR和数字PCR检测鉴定水稻细菌性条斑病菌 Development of Droplet Digital PCR Assay for Detection of Seed-Borne Burkholderia glumae and B. gladioli Causing Bacterial Panicle Blight Disease of Rice Developing a multiplex PCR-based assay kit for bloodstream infection by analyzing genomic big data Inhibitory Effect and Mechanism of Trichoderma taxi and Its Metabolite on Trichophyton mentagrophyte 基因VI 型新城疫病毒反转录数字PCR检测方法的建立与应用 Interlaboratory assessment of quantification of SARS-CoV-2 RNA by reverse transcription digital PCR 3.Methodology A Strategy for the Production and Molecular Validation of Agrobacerium-Mediated Intragenic Octoploid Strawberry 4.Other A PAM-free CRISPRCas12a ultra-specific activation mode based on toehold-mediated strand displacement and branch migration